Basic Sciencemoderate evidence

Systematic profiling reveals betaine as an exercise mimetic for geroprotection.

Cell·September 18, 2025·PMID 40570836

Why it matters

This paper uncovers a molecular mechanism—betaine-mediated TBK1 inhibition—by which exercise combats aging. It opens the door to betaine as a targeted intervention for age-related decline, relevant for specialists focused on longevity and metabolic health.

Infographic summary of Systematic profiling reveals betaine as an exercise mimetic for geroprotection.
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