Randomized Trialhigh evidence

Pasteurized Akkermansia muciniphila MucT for weight loss maintenance in people with overweight and obesity: a controlled randomized trial.

Nature medicine·May 13, 2026·PMID 42120725

Why it matters

Weight regain after diet-induced loss is a major clinical challenge. This study provides early evidence that a specific gut microbe supplement may help sustain weight loss, offering a novel, potentially safe adjunct to lifestyle interventions.

Infographic summary of Pasteurized Akkermansia muciniphila MucT for weight loss maintenance in people with overweight and obesity: a controlled randomized trial.
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