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Plasma proteomics defines two reproducible subphenotypes of sepsis-associated acute kidney injury with distinct outcomes.
Nature communications·August 19, 2026·PMID 42844256
Why it mattersSepsis-associated acute kidney injury is heterogeneous, and previous treatment trials have failed. This proteomic classification identifies a high-risk inflammatory subgroup that may respond to targeted therapy, potentially enabling precision medicine in critical care.
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