Meta-Analysishigh evidence
Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementias.
Nature genetics·June 1, 2026·PMID 42237039
Why it mattersExpands the genetic landscape of ADRD, offering new targets for risk stratification and biological investigation. The polygenic score's link to neuropathology supports its potential utility in identifying individuals at higher risk for Alzheimer's-specific brain changes.

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