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A comparison of the efficacy and safety of direct oral anticoagulants with low molecular weight heparin for venous thromboembolism prophylaxis after total hip arthroplasty : a systematic review and meta-analysis.

The bone & joint journal·November 1, 2026·PMID 42966367

Why it matters

VTE prophylaxis after total hip arthroplasty balances thrombotic and bleeding risks. This analysis suggests DOACs may offer better VTE prevention than LMWH without excess bleeding when using UK-licensed regimens, potentially simplifying oral prophylaxis and reducing healthcare costs.

Infographic summary of A comparison of the efficacy and safety of direct oral anticoagulants with low molecular weight heparin for venous thromboembolism prophylaxis after total hip arthroplasty : a systematic review and meta-analysis.
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