Randomized Trialhigh evidence

Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury.

The New England journal of medicine·October 14, 2026·PMID 42873070

Why it matters

The choice of initial renal-replacement modality in critically ill patients with acute kidney injury has long been debated. This trial provides high-level evidence that intermittent hemodialysis may be associated with higher mortality than continuous therapy, potentially influencing clinical decision-making in intensive care settings.

Infographic summary of Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury.
Visual abstract · MedLit

The papers that matter, first.

MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.

§

MedLit · Evidence, Distilled