Randomized Trialhigh evidence
Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury.
The New England journal of medicine·October 14, 2026·PMID 42873070
Why it mattersThe choice of initial renal-replacement modality in critically ill patients with acute kidney injury has long been debated. This trial provides high-level evidence that intermittent hemodialysis may be associated with higher mortality than continuous therapy, potentially influencing clinical decision-making in intensive care settings.

The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled