Meta-Analysishigh evidence
The Human Dorsolateral Prefrontal Cortex in Pain and Pain Modulation: A Review and Activation-Likelihood Estimation Approach.
European journal of pain (London, England)·July 1, 2026·PMID 42340106
Why it mattersFor neurologists and pain specialists, this provides the most anatomically precise map of dlPFC engagement in pain perception and modulation, informing target selection for non-invasive brain stimulation therapies.

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