Systematic Reviewmoderate evidence
Accelerating Decline in Serum Testosterone across Birth Cohorts: A Systematic Review and Meta-Regression Analysis.
The world journal of men's health·September 28, 2026·PMID 42845169
Why it mattersDeclining testosterone levels in younger, normal-weight men may signal broader shifts in male reproductive health and could affect clinical interpretation of testosterone values across generations. Understanding this trend helps clinicians contextualize individual results and consider age- and cohort-specific norms.
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