Randomized Trialhigh evidence

A Prospective, Randomized, Controlled Clinical Trial of High-Frequency Electromagnetic Coupling Powered Permanent Peripheral Nerve Stimulator for the Treatment of Chronic Craniofacial Pain.

Pain physician·September 1, 2025·PMID 40986904

Why it matters

This study provides Level 1 evidence for a permanent PNS option in refractory craniofacial pain, a condition with limited effective treatments. The high responder rate and durability of effect address a significant unmet need for patients who fail conservative therapies.

Infographic summary of A Prospective, Randomized, Controlled Clinical Trial of High-Frequency Electromagnetic Coupling Powered Permanent Peripheral Nerve Stimulator for the Treatment of Chronic Craniofacial Pain.
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