Randomized Trialhigh evidence

Economic Outcomes and Quality of Life After CABG or PCI for Multivessel Disease: The FAME 3 Trial.

Journal of the American College of Cardiology·April 28, 2026·PMID 41194756

Why it matters

This trial provides contemporary evidence that FFR-guided PCI with modern drug-eluting stents offers equivalent quality of life at substantially lower cost than CABG for multivessel disease, challenging traditional assumptions about revascularization strategy value.

Infographic summary of Economic Outcomes and Quality of Life After CABG or PCI for Multivessel Disease: The FAME 3 Trial.
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