Randomized Trialhigh evidence
Economic Outcomes and Quality of Life After CABG or PCI for Multivessel Disease: The FAME 3 Trial.
Journal of the American College of Cardiology·April 28, 2026·PMID 41194756
Why it mattersThis trial provides contemporary evidence that FFR-guided PCI with modern drug-eluting stents offers equivalent quality of life at substantially lower cost than CABG for multivessel disease, challenging traditional assumptions about revascularization strategy value.

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