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Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice.

Nature aging·July 24, 2026·PMID 42498891

Why it matters

Dietary interventions targeting specific branched-chain amino acids may offer a translational strategy to improve healthspan and longevity. Valine restriction emerges as a candidate with sex-specific effects, highlighting the need to consider biological sex in nutritional geroscience.

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