Randomized Trialhigh evidence

Treatment With 9-mg Mazdutide for Weight Reduction in Chinese Adults With Obesity: The GLORY-2 Randomized Clinical Trial.

JAMA·June 7, 2026·PMID 42251595

Why it matters

Mazdutide is a novel dual glucagon/GLP-1 receptor agonist that produced substantial weight loss in a Chinese population with obesity. This adds to the growing armamentarium of incretin-based therapies and may offer an alternative for patients who do not tolerate or respond to existing agents.

Infographic summary of Treatment With 9-mg Mazdutide for Weight Reduction in Chinese Adults With Obesity: The GLORY-2 Randomized Clinical Trial.
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