Meta-Analysishigh evidence
Buprenorphine-based treatments outcomes in pregnant opioid-dependent women: A systematic review and meta-analysis.
Addiction (Abingdon, England)·May 1, 2026·PMID 41345707
Why it mattersOpioid use disorder in pregnancy is a critical clinical issue. This meta-analysis provides pooled evidence that buprenorphine, particularly buprenorphine-naloxone, may reduce NAS severity and treatment needs compared to methadone, informing medication-assisted treatment decisions for pregnant patients.
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