Cohort Studymoderate evidence
Metabolomic signatures of extreme old age: findings from the New England Centenarian Study.
GeroScience·March 27, 2026·PMID 41888502
Why it mattersIt identifies specific metabolites and pathways—such as bile acids, NAD+ metabolism, and oxidative stress—that may underlie healthy aging, offering potential biomarkers and targets for interventions aimed at extending healthspan.
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