Randomized Trialhigh evidence

Intra-Arterial thrombolysis after SUCCESSful angiographic recanalization in acute large-vessel occlusion stroke of the anterior circulation (IA-SUCCESS): a multicentre, randomised, clinical trial protocol.

European stroke journal·July 6, 2026·PMID 42439416

Why it matters

Successful recanalization does not always restore microvascular perfusion, and IAT may improve tissue reperfusion and clinical outcomes. This trial will provide high-quality randomized data in a European population, addressing a gap left by prior Asian studies and potentially refining post-thrombectomy management.

Infographic summary of Intra-Arterial thrombolysis after SUCCESSful angiographic recanalization in acute large-vessel occlusion stroke of the anterior circulation (IA-SUCCESS): a multicentre, randomised, clinical trial protocol.
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