Randomized Trialhigh evidence

Effects of daily multivitamin-multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial.

Nature medicine·March 1, 2026·PMID 41803341

Why it matters

This is the first large RCT to show that a common, inexpensive MVM supplement may slow epigenetic aging, providing a plausible mechanism for previously observed reductions in age-related chronic conditions.

Infographic summary of Effects of daily multivitamin-multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial.
Visual abstract · MedLit

The papers that matter, first.

MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.

§

MedLit · Evidence, Distilled