Meta-Analysishigh evidence
Varenicline for e-cigarette (vaping) cessation: Systematic review and meta-analysis of randomized controlled trials.
Journal of substance use and addiction treatment·August 1, 2026·PMID 41991082
Why it mattersE-cigarette cessation lacks evidence-based pharmacotherapies. This analysis provides the strongest evidence to date that varenicline is effective and tolerable for vaping cessation, offering addiction specialists a potential off-label option for a growing clinical need.
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