Randomized Trialhigh evidence
Brain Structures and Cognitive Decline: Moderation Analysis of the PACt-MD Randomized Clinical Trial of Brain Stimulation Plus Cognitive Remediation in Older Adults With Remitted Depression or Mild Cognitive Impairment.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·August 1, 2026·PMID 42203570
Why it mattersIdentifying which patients are most likely to benefit from cognitive remediation plus tDCS could improve patient selection and resource allocation in dementia prevention, especially given the heterogeneity of treatment response in at-risk populations.
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