Cohort Studymoderate evidence
Administration of Preoperative Cryoneurolysis Is Associated With Continued and Persistent Opioid Reduction and Improved Outcomes in Primary Total Knee Arthroplasty.
The Journal of arthroplasty·August 15, 2026·PMID 42600867
Why it mattersOpioid stewardship in joint replacement is a priority, and cryoneurolysis offers a non-opioid, percutaneous option that may reduce opioid exposure and improve recovery when integrated into multimodal pathways.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled