Cohort Studymoderate evidence
Dehydroepiandrosterone Sulfate/Cortisol Ratio as a Biomarker of Depressive Symptoms in Late-Onset Hypogonadism: An Analysis of 3,005 Males.
The world journal of men's health·June 9, 2026·PMID 42402869
Why it mattersThis study highlights a neuroendocrine biomarker that may better reflect mood disturbances in men with LOH than testosterone alone, offering a potential tool for psychological assessment in performance and longevity practice.

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