Randomized Trialhigh evidence

Evaluating the Impact of Urolithin A Supplementation on Running Performance, Recovery, and Mitochondrial Biomarkers in Highly Trained Male Distance Runners.

Sports medicine (Auckland, N.Z.)·December 1, 2025·PMID 40839339

Why it matters

Urolithin A may aid recovery and reduce perceived effort in endurance athletes, even without immediate performance gains. The observed improvements in VO2max and muscle damage markers, along with mitochondrial pathway upregulation, suggest potential for long-term training adaptations.

Infographic summary of Evaluating the Impact of Urolithin A Supplementation on Running Performance, Recovery, and Mitochondrial Biomarkers in Highly Trained Male Distance Runners.
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