Randomized Trialhigh evidence
The effect of pre-exercise hyperventilation on repeated high-intensity inclined sprint performance.
Experimental physiology·July 1, 2026·PMID 42185035
Why it mattersPre-exercise hyperventilation is sometimes promoted to buffer exercise-induced acidosis and enhance high-intensity performance, but this well-controlled study shows no benefit in a real-world applicable protocol for incline sprints. The negative subjective experience further argues against its use.

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