Systematic Reviewvery high evidence
Electronic cigarettes for smoking cessation.
The Cochrane database of systematic reviews·August 26, 2026·PMID 42642048
Why it mattersSmoking cessation is a critical intervention in addiction medicine and internal medicine, and clinicians need evidence-based options. This review provides high-certainty evidence that nicotine EC are more effective than NRT for quitting, which may inform shared decision-making with patients who have struggled with traditional therapies.

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