Randomized Trialhigh evidence
Safety, tolerability and subjective effects of vaporized N,N-Dimethyltryptamine: A randomized double-blind clinical trial.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology·August 1, 2025·PMID 40532423
Why it mattersAs psychedelic therapies gain traction, understanding the safety and subjective profile of short-acting agents like vaporized DMT is critical for clinical development. This study offers the first randomized controlled data on inhaled DMT, informing its potential role in psychedelic-assisted therapy.
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