Cohort Studymoderate evidence
Differential Effect of Endovascular Treatment in Medium or Distal Vessel Occlusion: A Distal Secondary Analysis.
Stroke·October 30, 2026·PMID 42961033
Why it mattersPatients with medium or distal vessel occlusion stroke are heterogeneous, and overall trial results showing no EVT benefit may obscure subgroups where EVT is harmful or neutral. This analysis identifies a subgroup—those likely to do well with medical therapy alone—where EVT may worsen outcomes, informing patient selection and avoiding unnecessary intervention.

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