Randomized Trialhigh evidence
Time of day influences caffeine's effects on exercise-induced haemostatic responses in sedentary young men: a randomized crossover trial.
European journal of clinical nutrition·May 1, 2026·PMID 41998349
Why it mattersFor specialists counseling patients on exercise and cardiovascular risk, this study highlights that the timing of exercise and caffeine consumption may modulate thrombotic risk, particularly in sedentary individuals. It provides mechanistic insight into circadian variations in haemostasis during physical activity.

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