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Testosterone replacement therapy increases 2 and 5 year reoperation rates after posterior lumbar fusion: a propensity-matched analysis of 1808 surgical patients.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·September 1, 2026·PMID 42172893
Why it mattersWith rising TRT use, spine surgeons need evidence to counsel patients on long-term surgical expectations. This study identifies TRT as a potential marker for higher reoperation risk, aiding in risk stratification and postoperative surveillance.

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