Randomized Trialhigh evidence
Effects of low-dose esketamine on early quality of recovery following minimally invasive esophagectomy: a multicenter, randomized controlled study.
Annals of medicine·December 1, 2026·PMID 42484088
Why it mattersMinimally invasive esophagectomy patients often suffer significant postoperative pain and psychological distress, which can delay recovery. This trial provides evidence that a simple intraoperative esketamine infusion can enhance patient-centered recovery, offering anesthesiologists a tool to improve early outcomes in this high-risk population.
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