Randomized Trialhigh evidence

36-Month prospective multicenter randomized controlled trial comparing endoscopic facet denervation and cryoneurolysis for chronic lumbar facet joint pain.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·September 4, 2026·PMID 42696034

Why it matters

For interventional pain and spine specialists, this trial provides long-term comparative data on two established denervation techniques for facet-mediated low back pain. The lack of significant difference in pain outcomes at 36 months suggests that either procedure can be considered, with reintervention rates and procedural factors potentially guiding choice.

Infographic summary of 36-Month prospective multicenter randomized controlled trial comparing endoscopic facet denervation and cryoneurolysis for chronic lumbar facet joint pain.
Visual abstract · MedLit

The papers that matter, first.

MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.

§

MedLit · Evidence, Distilled