Cohort Studyhigh evidence
Multi-omic definition of metabolic obesity through adipose tissue-microbiome interactions.
Nature medicine·January 1, 2026·PMID 41482560
Why it mattersBMI fails to capture metabolic heterogeneity in obesity, leading to misclassification of cardiometabolic risk. metBMI provides a more precise, biologically grounded stratification tool that integrates adipose tissue dysfunction and gut microbiome interactions, potentially guiding personalized interventions in metabolic health, weight management, and bariatric surgery.

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