Meta-Analysishigh evidence
Effects of perioperative benzodiazepine administration on postoperative patient-reported outcomes: a systematic review and meta-analysis of randomised controlled trials.
British journal of anaesthesia·December 1, 2025·PMID 41152051
Why it mattersBenzodiazepines are commonly used perioperatively to improve patient experience, but this large synthesis challenges that assumption, suggesting they may not improve and could worsen anxiety, with no benefit for pain, recovery quality, or satisfaction.

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