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Sleep-Related and Chronobiology Traits and Health-Related Phenotypes: A Phenome-Wide Mendelian Randomisation Study.

Journal of sleep research·July 28, 2026·PMID 42517234

Why it matters

Sleep and circadian traits are modifiable risk factors that may causally influence a wide range of chronic diseases, including cardiovascular, mental health, and musculoskeletal disorders. Understanding these genetic links helps clinicians prioritize sleep interventions for disease prevention and patient counseling.

Infographic summary of Sleep-Related and Chronobiology Traits and Health-Related Phenotypes: A Phenome-Wide Mendelian Randomisation Study.
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