Randomized Trialhigh evidence

Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial.

JAMA·June 3, 2025·PMID 40266580

Why it matters

Youth vaping is highly prevalent, yet evidence-based pharmacotherapy is lacking. This trial provides strong evidence that varenicline, combined with counseling, can substantially increase vaping cessation in this population, addressing a critical treatment gap.

Infographic summary of Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial.
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