Randomized Trialhigh evidence
Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial.
JAMA·June 3, 2025·PMID 40266580
Why it mattersYouth vaping is highly prevalent, yet evidence-based pharmacotherapy is lacking. This trial provides strong evidence that varenicline, combined with counseling, can substantially increase vaping cessation in this population, addressing a critical treatment gap.

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