Randomized Trialhigh evidence
Full-spectrum extract from Cannabis sativa DKJ127 for chronic low back pain: a phase 3 randomized placebo-controlled trial.
Nature medicine·December 1, 2025·PMID 41023483
Why it mattersChronic low back pain is highly prevalent and current treatments have limited efficacy and safety concerns. This large, rigorous trial provides evidence that a standardized cannabis extract can offer modest but statistically significant pain relief, particularly for patients with a neuropathic component.
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