Meta-Analysishigh evidence
Factor XIa Inhibitors for Secondary Prevention After Noncardioembolic Stroke: A Systematic Review and Meta-Analysis.
Neurology·October 13, 2026·PMID 42748394
Why it mattersPatients with noncardioembolic stroke or TIA remain at risk for recurrence despite antiplatelet therapy. FXIa inhibitors may offer additional protection without the bleeding trade-off seen with other anticoagulants, addressing a key unmet need in secondary stroke prevention.
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