Randomized Trialhigh evidence

Clinician-guided digital CBT-I improves sleep quality and apnea severity in patients with co-morbid insomnia and OSA: A Double-Blind, Randomized Clinical Trial.

American journal of respiratory and critical care medicine·October 29, 2026·PMID 42958645

Why it matters

COMISA is common and challenging to treat, and traditional CBT-I may be difficult to access. This trial shows that a scalable, clinician-guided digital format can improve both insomnia and OSA severity, offering a practical option for sleep and internal medicine practices.

Infographic summary of Clinician-guided digital CBT-I improves sleep quality and apnea severity in patients with co-morbid insomnia and OSA: A Double-Blind, Randomized Clinical Trial.
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