Meta-Analysishigh evidence
Platelet-rich plasma outcomes in knee osteoarthritis are associated with the amount of total deliverable platelets: A systematic review and meta-analysis.
PM & R : the journal of injury, function, and rehabilitation·February 1, 2026·PMID 40980837
Why it mattersPRP is widely used for knee OA, but optimal dosing is unclear. This analysis provides dose-specific effect estimates, helping clinicians select PRP preparations that may maximize functional benefit while avoiding potential diminishing returns at very high platelet counts.
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