Randomized Trialhigh evidence
Prolozone M Therapy's Analgesic Efficacy for Managing Moderate-to-Severe Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial.
Pain physician·September 1, 2026·PMID 42804311
Why it mattersFor patients with advanced knee osteoarthritis who decline or cannot access arthroplasty, a safe, non-surgical injectable that provides durable analgesia and possible chondroprotection could expand treatment options beyond corticosteroids, which often have limited long-term benefit.
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