Meta-Analysishigh evidence
Sodium Bicarbonate for Acute Metabolic Acidosis in Critically Ill Adults: A Meta-Analysis of Randomized Clinical Trials.
Critical care medicine·May 22, 2026·PMID 42171427
Why it mattersAcute metabolic acidosis is common in the ICU, and decisions about bicarbonate therapy have been controversial. This analysis provides robust evidence that bicarbonate reduces RRT use, which can inform clinical protocols and resource utilization in critical care.
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