Cohort Studymoderate evidence
Interaction Between COMT Genotype and MIND Diet, Cognitive Decline, and Incident Dementia: A Prospective Cohort Study.
Nutrients·September 30, 2026·PMID 42884681
Why it mattersDietary prevention of cognitive decline may be genotype-dependent, with COMT activity influencing response to MIND diet polyphenols. This suggests personalized nutrition strategies could target those most likely to benefit.
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