Randomized Trialhigh evidence

Efficacy and cost effectiveness of high volume injections with and without corticosteroid compared with sham for midportion Achilles tendinopathy (Inject trial): randomised controlled trial.

BMJ (Clinical research ed.)·October 28, 2026·PMID 42951276

Why it matters

High volume injections are commonly used for Achilles tendinopathy despite limited evidence. This trial provides robust data that they do not improve long-term outcomes over sham, and corticosteroid may even worsen longer-term results, informing treatment decisions and guideline recommendations.

Infographic summary of Efficacy and cost effectiveness of high volume injections with and without corticosteroid compared with sham for midportion Achilles tendinopathy (Inject trial): randomised controlled trial.
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