Randomized Trialhigh evidence
Multivessel coronary artery bypass grafting via small thoracotomy versus sternotomy (MIST): an investigator-initiated, international, open-label, randomised controlled trial.
Lancet (London, England)·July 31, 2026·PMID 42537680
Why it mattersFor patients with multivessel disease requiring CABG, minimally invasive approaches may offer faster physical recovery without compromising early safety, but randomized data have been lacking. This trial provides evidence that MICS CABG improves patient-reported outcomes at 1 month when performed by experienced teams.
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