Randomized Trialhigh evidence

Intraoperative Zoledronic Acid for Arthroscopic Rotator Cuff Repair: Short-Term Results From a Prospective, Randomized, Placebo-Controlled Phase II Trial.

The American journal of sports medicine·February 1, 2026·PMID 41549490

Why it matters

Rotator cuff retears remain a common and challenging complication. A simple, low-cost intraoperative intervention that reduces retears and improves early functional recovery could directly impact surgical outcomes and patient counseling.

Infographic summary of Intraoperative Zoledronic Acid for Arthroscopic Rotator Cuff Repair: Short-Term Results From a Prospective, Randomized, Placebo-Controlled Phase II Trial.
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