Randomized Trialhigh evidence
Duration of Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest: The ICECAP Randomized Clinical Trial.
JAMA·August 5, 2026·PMID 42554995
Why it mattersOptimal duration of therapeutic hypothermia after cardiac arrest has been uncertain, with practice varying widely. This large, rigorous trial provides strong evidence that prolonging cooling beyond 6 hours does not improve neurological recovery, potentially simplifying post-arrest care and reducing resource utilization.

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