Randomized Trialhigh evidence
Elastance as a determinant of the effect of prone positioning on mortality in acute respiratory distress syndrome: a post hoc analysis of the PROSEVA trial.
Critical care (London, England)·May 16, 2026·PMID 42143375
Why it mattersProne positioning is a cornerstone of ARDS management, but patient selection remains imprecise. This analysis suggests that baseline respiratory system elastance should not be used to decide which patients receive prone positioning, as it does not identify a subgroup with differential mortality benefit.
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