Cohort Studyhigh evidence
Elevated cardiovascular risk associated with hormone replacement therapy: A comprehensive analysis of reproductive factors and atherosclerotic cardiovascular disease outcomes in the UK Biobank cohort.
Acta obstetricia et gynecologica Scandinavica·August 20, 2026·PMID 42619552
Why it mattersHRT prescribing decisions require balancing menopausal symptom relief against cardiovascular safety. This large cohort quantifies ASCVD risk and identifies subgroups—perimenopausal, younger, and those with late reproductive milestones—where risk is most elevated, supporting individualized risk assessment.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled