Cohort Studymoderate evidence
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle.
Nature aging·July 1, 2026·PMID 42399371
Why it mattersIt provides molecular evidence that sustained exercise training can partially reverse age-related declines in muscle energy metabolism and preserve a more youthful molecular profile, which is directly relevant to clinicians focused on optimizing healthspan and physical performance in aging populations.

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