Randomized Trialhigh evidence

Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.

Journal of the International Society of Sports Nutrition·December 31, 2026·PMID 41863133

Why it matters

For clinicians focused on healthy aging and sarcopenia prevention, this trial suggests that pairing structured resistance training with essential amino acid supplementation may outperform either strategy alone in older women before overt frailty develops.

Infographic summary of Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.
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