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Preoperative Testosterone Replacement Therapy Is Associated With Increased Complication Risk After Total Knee Arthroplasty: A Propensity-Matched Analysis of 13,250 Patients.
The Journal of arthroplasty·July 1, 2026·PMID 41177190
Why it mattersTRT use is common in aging men undergoing arthroplasty, yet its perioperative safety profile is poorly defined. These findings highlight a potential modifiable risk factor that orthopedic surgeons and primary care providers should consider during preoperative optimization.
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