Randomized Trialhigh evidence

In elective cardiac surgery, perioperative dapagliflozin reduced acute kidney injury vs. placebo at 7 d.

Annals of internal medicine·November 3, 2026·PMID 42970797

Why it matters

Acute kidney injury is a common and serious complication after cardiac surgery, associated with worse outcomes. An SGLT2 inhibitor that reduces this risk could improve perioperative management.

Infographic summary of In elective cardiac surgery, perioperative dapagliflozin reduced acute kidney injury vs. placebo at 7 d.
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